Maggio 2016 - Volume XXXV - numero 5
Farmacoriflessioni
1Pediatra di famiglia, Mogliano Veneto (Treviso)
22UOC di Pediatria e Neonatologia, Ospedale di Ravenna, AUSL della Romagna
3UO di Nefrologia e Dialisi, Ospedale Pediatrico Bambin Gesù, Roma
4UO di Nefrologia e Dialisi Pediatrica, Clinica Pediatrica “G. e D. De Marchi”, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milano
5Servizio di Nefrologia e Dialisi, Clinica Pediatrica, IRCCS Materno-Infantile “Burlo Garofolo”, Trieste
Indirizzo per corrispondenza: vitalia.murgia@tin.it
Key words: Nephrotic cortico-sensitive syndrome, Nephrology, Cortisone, Steroid-saver
Nephrotic cortico-sensitive syndrome is a chronic disease difficult to manage. Indeed, it presents a relapse risk in about 90% of cases and it may develop steroid dependence/ frequent relapse in about 50% of children. The nephrologist and the paediatrician face with the difficult task of looking for the right treatment: first by administering the right dose of cortisone and subsequently by choosing the steroid-saver, if needed. The RCTs reported in a recent review published in Archives of Disease in Childhood suggest new perspectives on essential treatments. The present article outlines the essential aspects of said review and reports the relative comments of three Italian specialists in paediatric nephrology.
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