1SSD di Oncoematologia Pediatrica, Azienda Ospedaliero-Universitaria Sant’Anna, Ferrara
2SSD di Oncologia-Radioterapia dell'Adolescente e del Giovane, Centro di Riferimento Oncologico di Aviano (Pordenone)
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Key words: Hodgkin’s lymphoma, Long-term side effects, Chemotherapy, Radiotherapy
Children and adolescents affected by Hodgkin’s lymphoma (HL) show a high survival rate. More than any other patient population treated for other types of cancer, the longterm survivors from HL were the subject of studies on medium- and long-term side effects of chemotherapy and radiotherapy. These observations determined the improvement of treatment strategy in order to achieve higher cure rates with less toxicity. The paper describes the evolution and modification of HL therapy in the last 50 years, also according to the discovery of side effects.
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