Gennaio 2019 - Volume XXXVIII - numero 1
Pagine elettroniche
UOC di Pediatria e Neonatologia, Ospedale di Ravenna, AUSL della Romagna
*Scuola di specializzazione in Pediatria, Università di Ferrara
Indirizzo per corrispondenza: alessandraiacono@alice.it
Key words: Severe Campylobacter infection, Antibiotic therapy, Antibiotic resistance
Campylobacter infection is one of the most frequent enteritis in developed countries and in most cases it features a self-limiting character. In some cases it shows severe clinical pictures and it requires antibiotic therapy. Cases of antibiotic resistance are emerging, especially against fluoroquinolone. The article presents a case of a 14-year-old boy with a febrile Campylobacter enteritis treated with ceftriaxone and ciprofloxacin with an immediate resolution of the symptoms. Ten days later, the boy still showed the same symptoms suggesting three hypotheses: 1) failure of Campylobacter’s eradication; 2) abdominal abscess; 3) beginning of inflammatory bowel disease associated with a concomitant and confusing Campylobacter jejuni infection. Coproculture still showed the presence of Campylobacter, and the treatment with azithromycin was effective in eradicating the infection. Past history and complete negativity of inflammatory index and faecal calprotectin allowed an inflammatory bowel disease to be excluded.
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Pagine elettroniche
1Scuola di Specializzazione in Pediatria, Università di Modena e Reggio Emilia
2Struttura complessa di Neonatologia; 3Struttura complessa di Pediatria, Azienda Ospedaliera e Universitaria Policlinico di Modena
Indirizzo per corrispondenza: carolinabariola@hotmail.it
Key words: Floppy infant, Feeding problems, Dysmorphism, Prader-Willi syndrome
The paper describes the case of a term newborn infant, born by elective caesarean section with no prenatal and perinatal risk factors. He presented with an unexpected cardiorespiratory depression at birth, severe hypotonia, feeding problems and peculiar dysmorphism: micrognathia with chubby cheeks, small hands and right cryptorchidism. In the suspect of Prader-Willi syndrome, DNA methylation test confirmed the diagnostic hypothesis. The simultaneous presence of neonatal hypotonia, poor suck and peculiar dysmorphism should suggest Prader-Willi syndrome and thus the performance of the DNA methylation test to confirm the diagnosis for a timely and adequate therapeutic work-up.
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